Antibacterial Activities and Mechanism of Action of Acetone Extracts from Rabdosia rubescens

Antibacterial Activities and Mechanism of Action of Acetone Extracts from Rabdosia rubescens

Rabdosia rubescens; Extracts; Antibacterial activity; Mechanism of action

The antibacterial activities and mechanism of action of acetone extracts from R. rubescens were reported in this paper. The results showed that 80% acetone extracts had both the highest contents of total phenolics and flavonoids. Acetone extracts showed better antibacterial activities against Gram-positive bacterial strains and there were no inhibitory effects found on tested Gram-negative bacteria. In addition, 80% acetone extracts from R. rubescens had relatively higher antibacterial activities with the lowest values of MIC and MBC at 2.5 mg/mL and 5 mg/mL against B. subtilis. The antibacterial mechanism of 80% acetone extracts against Bacillus subtilis might be described as disrupting cell wall, increasing cell membrane permeability, and finally leading to the leakage of cell constituents

Cheng, Li Ping; College of Life Sciences, Shanxi Normal University, Linfen 041004, China

Hu, Qing Ping; College of Life Sciences, Shanxi Normal University, Linfen 041004, China

Aceh International Journal of Science and Technology; Vol 4, No 1 (2015): January - April 2015

2088-9860

Graduate School of Syiah Kuala University

2014-12-27

http://jurnal.unsyiah.ac.id/AIJST/article/view/2100/pdf_9

application/pdf

eng

info:eu-repo/semantics/article

info:eu-repo/semantics/publishedVersion

Peer-reviewed Article

http://jurnal.unsyiah.ac.id/AIJST/article/view/2100

10.13170/aijst.4.1.2100