Tyrosinase Inhibition Type of Isolated Compounds Obtained from Pachyrhizus erosus

Dublin Core

Title

Tyrosinase Inhibition Type of Isolated Compounds Obtained from Pachyrhizus erosus

Description

Abstract - In Indonesia, Bengkoang (Phacyrhizus erosus) have been used as one of cosmetics especially as sun screening and skin whitening materials. Six active compounds in Bengkoang with antioxidant and skin whitening activities have been isolated, namely daidzein, daidzin, genistin, (8,9)-furanyl-pterocarpan-3-ol, 4-(2-(furane-2-yl)ethyl)-2-methyl-2,5-dihydro-furane-3-carbaldehyde and 2-butoxy-2,5-bis(hydroxymethyl)-tetrahydrofurane-3,4-diol. According to literatures, the type of their tyrosinase inhibitory activity has not yet reported. The determination of whitening activity of each compound was evaluated by the evaluation of Lineweaver-Burk plot. The result showed that five compounds had competitive inhibitory activity and 8,9-furanyl-pterocarpan-3-ol showed a non-competitive inhibition. Keywords: Pachyrhizus erosus, tyrosinase, competitive inhibition and non-competitive inhibition

Creator

Lukitaningsih, Endang
Bahi, Muhammad
Holzgrabe, Ulrike

Source

Aceh International Journal of Science and Technology; Vol 2, No 3: September - December 2013
2088-9860

Publisher

Graduate School of Syiah Kuala University

Date

2014-01-02

Relation

http://jurnal.unsyiah.ac.id/AIJST/article/view/1063/999

Format

application/pdf

Language

eng

Type

info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article

Identifier

http://jurnal.unsyiah.ac.id/AIJST/article/view/1063
10.13170/aijst.2.3.1063