GAS CROMATOGRAPHIC ANALYSIS OF ORGANOPHOSPATE AND PYRETROID COMPOUNDS IN MOSQUITO COILS

GAS CROMATOGRAPHIC ANALYSIS OF ORGANOPHOSPATE AND PYRETROID COMPOUNDS IN MOSQUITO COILS

Mosquito coils contain active compounds such as chlorpyriphos, dichlorphos, and d-alletrhrin which may be hazardous to the health. As majority of pesticides are stable heat, they can be changed into stable vapor state by column.  a gas chromatographic method of analysis was developed. Gas chromatography for organophosphate compounds, namely chlorpyriphos and dichlorphos, with a OV-17 packed column, and a flame photometry detector equipped by filter for phosphor, which detecs phosphor containing compounds exclusively, avoiding any interference of other non phosphor compounds present in the sample matrix. Gas chromatography for a pyrethoid compound, d-allethrin, utilizes a HP-1 capilarry column with a flame ionization detector, and detect, any ionizable compound. The research was initiated by adjustment of the condition of gas chromatography system to obtain an appropiate separation of compounds a good shape of chromatogram and a tolerable retention time.  With a flow rate of nitrogen 55 ml/min, column temperatures of 210oC, a detector and injector temperature of 230oC, the method gave a retention times chlorpyriphos of 6,47 minute and that of dichlorphos of 0,73 minute . The difference in retention time of chlorpyriphos and that of dichlorphos was caused by the difference in molecular weight of both compounds, thin dichlorphos with a smaller molecular weight (220, 98) was eluted faster than chlorpyriphos (350,6). For  d-allethrin whit a flow rate of nitrogen gas of 40 ml/min, a column temperature  of 180oC, a detector and injector temperature of 210oC, a retention time of d-allethrin of 3,28 minutes was obtained. The mosquito coils tested did not contain any chlorpyriphos nor dichlorphos, and some contained d-allethrin. The d-allethrin content obtained in one of the sample was beyond the tolerated limit.

Sadli, Sadli; Program Study of Pharmacy, Department of Chemistry, Faculty of Mathematics and Natural Sciences, Syiah Kuala University, Banda Aceh

Misrahanum, Misrahanum; Program Study of Pharmacy, Department of Chemistry, Faculty of Mathematics and Natural Sciences, Syiah Kuala University, Banda Aceh

Jurnal Natural; Volume 11, Number 2, Year 2011

Jurnal Natural

2013-05-17

http://jurnal.unsyiah.ac.id/natural/article/view/597/506

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Peer-reviewed Article

http://jurnal.unsyiah.ac.id/natural/article/view/597