Isolasi dan karakterisasi senyawa metabolit sekunder dari bakteri laut Streptomyces sp.

Isolasi dan karakterisasi senyawa metabolit sekunder dari bakteri laut Streptomyces sp.

Abstract: Streptomyces is one of bacterial genus which has been considered as a potential source of many novel antibiotics from both terrestrial and marine microorganism. In this paper, four secondary metabolites have been isolated and characterized from a marine Streptomyces sp. B5798, namely phydroxyphenylacetic acid (2), indole-3-carboxylic acid (3), indole-3-acetic acid (4), and Macrolactin A (5), respectively. Two of them are common compounds, namely indole-3-carboxylic acid (3) and indole-3-acetic acid (4). The 3,4 dihydroxybenzaldehyde is a degradation product of phydroxyphenylacetic (2) in microorganism. Macrolactin A (5) showed cytotoxicity against brine shrimps test (A. salina). All structures of the isolated compounds were elucidated based on spectroscopic and mass spectrometry data.

Bahi, Muhammad; Jurusan Kimia, Fakultas Matematika dan Ilmu Pengetahuan Alam, Univesitas Syiah Kuala, Banda Aceh, 23111 Indonesia.

DEPIK; Vol 1, No 3: September - December 2012

2089-7790

Faculty of Marine and Fisheries, Syiah Kuala University

2012-12-01

http://jurnal.unsyiah.ac.id/depik/article/view/105/98

application/pdf

eng

info:eu-repo/semantics/article

info:eu-repo/semantics/publishedVersion

Peer-reviewed Article

http://jurnal.unsyiah.ac.id/depik/article/view/105

10.13170/depik.1.3.105