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                <text>FITRI YUNITA SARI</text>
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                <text>ABSTRAKNama: Fitri Yunita SariProgram Studi: Kedokteran GigiJudul: Pengaruh Ekstrak Buah Jamblang (Syzygium cumini) terhadap Pertumbuhan Candida albicans sebagai penyebab Kandidiasis Rongga Mulut .secara In Vitro. Kandidiasis adalah penyakit jaringan lunak dalam rongga mulut yang disebabkan oleh golongan jamur yaitu Candida albicans. Berbagai penelitian dilakukan dengan tujuan untuk menemukan bahan terapi yang aman untuk mencegah terjadinya kandidiasis, salah satunya adalah dengan menggali potensi tanaman herbal seperti buah jamblang (Syzygium cumini). Buah jamblang berpotensi mencegah kandidiasis karena tanaman ini memiliki efek farmakologik yaitu sebagai antifungi. Oleh karena itu tujuan dilakukan penelitian ini adalah untuk mengetahui pengaruh ekstrak buah jamblang (Syzygium cumini) terhadap pertumbuhan Candida albicans. Penelitian ini dilakukan dengan cara menguji ekstrak buah jamblang (Syzygium cumini)  yang diekstraksi dengan menggunakan alkohol 96% pada konsentrasi 25% sampai dengan 100%. Pertumbuhan koloni Candida albicans hasil uji dihitung dengan menggunakan metode perhitungan koloni (Plate Count Counter). Hasil penelitian menunjukkan bahwa ekstrak buah jamblang (Syzygium cumini) menghambat pertumbuhan Candida albicans. Konsentrasi minimum ekstrak buah jamblang (Syzygium cumini) dapat menghambat pertumbuhan Candida albicans adalah 25%, sedangkan konsentrasi maksimum adalah 100%. Adanya hambatan pertumbuhan diduga karena buah jamblang (Syzygium cumini) yang digunakan dalam penelitian ini mengandung minyak atsiri dan senyawa fenol yaitu flavonoid. Minyak atsiri dan flavonoid dari fenol dapat merusak membran sel, denaturasi protein, menghambat kerja enzim, dan mengganggu sintesis asam nukleat, sehingga hal inilah yang menyebabkan pertumbuhan jamur terganggu.Kata Kunci   : Kandidiasis, Candida albicans, ekstrak buah jamblang</text>
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                <text>Fakultas Kedokteran Gigi</text>
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                <text>CANDIDIASIS - MEDICINE</text>
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                <text>PENGARUH EKSTRAK BUAH JAMBLANG (SYZYGIUM CUMINI) TERHADAP PERTUMBUHAN CANDIDA ALBICANS SEBAGAI PENYEBAB KANDIDIASIS RONGGA MULUT SECARA IN VITRO</text>
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                <text>PENGARUH EKSTRAK BUAH MAHKOTA RNDEWA (PHALERIA MACROCARPA) TERHADAP DAYA RNTETAS TELUR IKAN KOI (CYPRINUS CARPIO)</text>
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                <text>Perdarahan merupakan salah satu komplikasi yang umumnya dapat terjadi pada prosedur dental seperti ekstraksi gigi atau prosedur bedah. Buah pepaya (Carica papaya L.) memiliki aktivitas farmakologis seperti antibakteri, antifungal, antiinflamasi, antimalaria, antihelmintik, dan juga sebagai antifertilitas. Penelitian ini bertujuan untuk mengetahui pengaruh ekstrak buah pepaya (Carica papaya L.) terhadap durasi perdarahan tikus Wistar (Rattus norvegicus). Penelitian eksperimental laboratoris ini menggunakan 10 ekor tikus Wistar (Rattus norvegicus) jantan dengan berat rata-rata 200-300 gram dan usia 8-12 minggu yang dibagi menjadi 2 kelompok, yaitu 5 ekor pada kelompok kontrol yang diberi perlakuan akuades setelah dibuat perlukaan pada ekor tikus dan 5 ekor pada kelompok perlakuan yang diberi ekstrak buah pepaya (Carica papaya L.). Durasi perdarahan diukur dengan menggunakan chronometer (Q&amp;Q 1/100 Chrono) dimulai dari detik terjadinya perdarahan sampai darah berhenti keluar dari luka ekor tikus. Hasil pengukuran rerata durasi perdarahan pada kelompok kontrol adalah 75,4 detik sedangkan kelompok perlakuan 41,2 detik. Hasil uji statistik T tidak berpasangan menunjukkan ekstrak buah pepaya berpengaruh secara bermakna dengan nilai signifikansi p=0,001 (p</text>
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                <text>Pengaruh ekstrak buha jamblang terhadap pertumbuhan streptococcus mutans sebagai agen utama penyebab karies</text>
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                <text>Enterococcus faecalis (E. faecalis) merupakan salah satu flora normal rongga mulut yang memiliki kemampuan invasi ke dalam tubulus dentin dan mampu bertahan dalam lingkungan asam dan basa dalam saluran akar. Beberapa penelitian menunjukkan bahwa bakteri tersebut resisten terhadap kalsium hidroksida. Daging buah mahkota dewa (Phaleria macrocarpa  (Scheff) Boerl.) merupakan salah satu tanaman herbal yang secara tradisional digunakan sebagai antibakteri. Efek antibakteri daging buah mahkota dewa timbul akibat adanya kandungan flavonoid, alkaloid, saponin, tanin, polifenol dan steroid. Tujuan penelitian ini adalah untuk mengetahui pengaruh ekstrak daging buah mahkota dewa (Phaleria macrocarpa  (Scheff) Boerl.) terhadap pertumbuhan E. faecalis. Enterococcus faecalis dikultur pada media CHROMAgar VRE Base (Non-vancomycin) dan diinkubasi pada suhu 370C dalam inkubator dengan suasana anaerob. Enterococcus faecalis selanjutnya dipaparkan dengan ekstrak etanol daging buah mahkota dewa untuk uji antibakteri menggunakan metode Standart Plate Count (SPC). Hasil analisis data menggunakan uji statistik one way ANOVA didapatkan nilai p=0,000 (p</text>
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                <text>PENGARUH EKSTRAK DAGING BUAH MAHKOTA DEWA (PHALERIA MACROCARPA (SCHEFF) BOERL.) TERHADAP PERTUMBUHAN ENTEROCOCCUS FAECALIS</text>
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