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                <text>Penggunaan tumbuhan alami yang berkhasiat obat mengalami perkembangan yang pesat.Rosella (Hibiscus sabdariffa L.) mengandung sejumlah senyawa kimia yang digunakan secara luasuntuk mengobati berbagai macam penyakit. Beberapa diantaranya adalah flavonoid, alkaloid, saponindan tanin yang berfungsi sebagai antibakteri. Tujuan dari penelitian ini adalah untuk mengetahuiaktivitas antibakteri ekstrak bunga Rosella terhadap Staphylococcus aureus dan Escherichia coli. BungaRosella diekstraksi dengan menggunakan pelarut etanol 96% dengan metode maserasi. Penelitian inimenggunakan Rancangan Acak Lengkap yang terdiri dari 4 kelompok perlakuan dan 2 kelompokkontrol dengan 3 kali pengulangan. Kelompok perlakuan terdiri dari konsentrasi ekstrak 12,5%, 25%,50% dan 75%. Kelompok kontrol terdiri dari kontrol positif (Amoksisilin 30 ?g sebagai kontrol positifStaphylococcus aureus dan Kloramfenikol 30 ?g sebagai kontrol positif Escherichia coli) dan kontrolnegatif (akuades steril). Uji aktivitas antibakteri dilakukan dengan metode difusi cakram Kirby-Bauer.Hasil penelitian menunjukkan bahwa ekstrak etanol bunga Rosella memiliki aktivitas antibakteri padakonsentrasi 12,5%, 25%, 50% dan 75% terhadap Staphylococcus aureus dengan diameter zona hambatrata-rata berturut-turut 13,67 mm, 17,67 mm, 22,67 mm, 25,33 mm dan terhadap Escherichia colidengan diameter zona hambat rata-rata berturut-turut adalah 6,33 mm, 10,67 mm, 17,67 mm, 19,67mm. Hasil analisis data dengan menggunakan Analysis Of Variance (ANOVA) dan dilanjutkan denganUji Duncan (P &lt; 0,01) menunjukkan bahwa ekstrak etanol bunga Rosella memiliki aktivitas antibakteriyang sangat nyata terhadap Staphylococcus aureus dan Escherichia coli dan semakin tinggi konsentrasi,semakin luas zona hambat yang terbentuk.Kata Kunci: Hibiscus sabdariffa L., aktivitas antibakteri, Staphylococcus aureus,Escherichia coli.</text>
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                <text>UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL BUNGA ROSELLA (HIBISCUS SABDARIFFA L.) TERHADAP ISOLAT KLINIS STAPHYLOCOCCUS AUREUS DAN ESCHERICHIA COLI SECARA IN VITRO</text>
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                <text>ABSTRACTTamarind (Tamarindus indica L.) is a plant that lives in the tropics and have various properties. One is as an antimicrobial properties. Tamarind leaves contain a variety of secondary metabolic compounds such as flavonoids, steroids, tannins and saponins. This study aims to determine the effect of ethanol extract of tamarind leaves in inhibiting the growth of Methicillin Resistant Staphylococcus aureus (MRSA) in vitro. Methodology: Experimental laboratory is using Complete Randomized Design (CRD) which is divided into 6 groups. Four treatment groups and two control groups. The treatment group consisted of ethanol extract of tamarind leaves with  concentration 75%, 50%, 25% and 12.5%. The control group consisted of vancomycin 30 mg as a positive control and sterile distilled water as negative control. Antibacterial activity test carried out by disc diffusion method. The parameters observed were inhibition zone diameter formed in the median. Data were analyzed by ANOVA and followed by the Smallest Real Differences Test (LSD) at ? = 0.05 level and translated according to the Grenwood classification &gt; 20 mm, 16-20 mm, 11-15mm and</text>
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                <text>Fakultas Kedokteran</text>
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                <text>UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL DAUN ASAM JAWA (TAMARINDUS INDICA L.) TERHADAP METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS SECARA IN VITRO</text>
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                <text>trisnawati</text>
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            <name>Date</name>
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                <text>2015</text>
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                <text>ABSTRACTTamarind (Tamarindus indica L.) is a plant that lives in the tropics and have various properties. One is as an antimicrobial properties. Tamarind leaves contain a variety of secondary metabolic compounds such as flavonoids, steroids, tannins and saponins. This study aims to determine the effect of ethanol extract of tamarind leaves in inhibiting the growth of Methicillin Resistant Staphylococcus aureus (MRSA) in vitro. Methodology: Experimental laboratory is using Complete Randomized Design (CRD) which is divided into 6 groups. Four treatment groups and two control groups. The treatment group consisted of ethanol extract of tamarind leaves with  concentration 75%, 50%, 25% and 12.5%. The control group consisted of vancomycin 30 mg as a positive control and sterile distilled water as negative control. Antibacterial activity test carried out by disc diffusion method. The parameters observed were inhibition zone diameter formed in the median. Data were analyzed by ANOVA and followed by the Smallest Real Differences Test (LSD) at ? = 0.05 level and translated according to the Grenwood classification &gt; 20 mm, 16-20 mm, 11-15mm and</text>
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                <text>Banda Aceh</text>
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                <text>UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL DAUN ASAM JAWA (TAMARINDUS INDICA L.) TERHADAP METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS SECARA IN VITRO</text>
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                <text>miftahul jannah</text>
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                <text>ABSTRACTTamarind (Tamarindus indica L.) is a plant that lives in the tropics and have various properties. One is as an antimicrobial properties. Tamarind leaves contain a variety of secondary metabolic compounds such as flavonoids, steroids, tannins and saponins. This study aims to determine the effect of ethanol extract of tamarind leaves in inhibiting the growth of Methicillin Resistant Staphylococcus aureus (MRSA) in vitro. Methodology: Experimental laboratory is using Complete Randomized Design (CRD) which is divided into 6 groups. Four treatment groups and two control groups. The treatment group consisted of ethanol extract of tamarind leaves with  concentration 75%, 50%, 25% and 12.5%. The control group consisted of vancomycin 30 mg as a positive control and sterile distilled water as negative control. Antibacterial activity test carried out by disc diffusion method. The parameters observed were inhibition zone diameter formed in the median. Data were analyzed by ANOVA and followed by the Smallest Real Differences Test (LSD) at ? = 0.05 level and translated according to the Grenwood classification &gt; 20 mm, 16-20 mm, 11-15mm and</text>
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                <text>Banda Aceh</text>
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                <text>http://etd.unsyiah.ac.id//index.php?p=show_detail&amp;id=11549</text>
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                <text>Fakultas Kedokteran</text>
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                <text>MEDICINAL PLANTS</text>
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                <text>UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL DAUN ASAM JAWA (TAMARINDUS INDICA L.) TERHADAP METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS SECARA IN VITRO</text>
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                <text>M. Rizky Fachri</text>
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                <text>Staphylococcus aureus adalah salah satu bakteri Gram positif penyebab infeksi pneumonia nosokomial. Bakteri ini sudah mulai resisten terhadap antibiotik methicillin sehingga dikenal adanya Methicilllin Resistant Staphylococcus aureus (MRSA). Alternatif pengobatan yang potensial ialah penggunaan senyawa antibakteri dari bahan alam salah satunya Momordica charantia. Tujuan dari penelitian ini adalah untuk mengetahui Konsentrasi Hambat Minimal (KHM) dan Konsentrasi Bunuh Minimal (KBM) ekstrak etanol Momordica charantia terhadap pertumbuhan MRSA isolat pneumonia nosokomial. Penelitian ini menggunakan Rancangan Acak Lengkap (RAL) yang terdiri dari 4 kelompok perlakuan dan 1 kelompok kontrol  Kelompok perlakuan terdiri dari ekstrak etanol Momordica charantia dengan konsentrasi 100, 200, 300, dan 400 mg/ml serta kelompok kontrol berupa suspensi MRSA dan akuades steril. Uji aktivitas antibakteri dilakukan dengan metode dilusi melalui pengamatan selisih optical density (?OD) untuk menentukan KHM dan pengamatan ada atau tidaknya pertumbuhan koloni pada media untuk menentukan KBM. Hasil penelitian ini didapatkan KHM ekstrak etanol Momordica charantia terhadap MRSA adalah 200 mg/ml dan KBM adalah 300 mg/ml. Analisis statistik dengan ANOVA yang dilanjutkan dengan uji Duncan untuk KHM dan uji Kruskal-Wallis untuk KBM (p &lt; 0,05) menunjukkan bahwa ekstrak etanol Momordica charantia mampu menghambat dan membunuh MRSA  isolat pneumonia nosokomial.Kata kunci: Momordica charantia, MRSA, KHM, KBM, pneumonia nosokomial</text>
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                <text>http://etd.unsyiah.ac.id//index.php?p=show_detail&amp;id=4854</text>
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                <text>UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL DAUN PARE (MOMORDICA CHARANTIA) TERHADAP METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS ISOLAT PNEUMONIA PASIEN RSUDZA SECARA DILUSI</text>
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