The effect of sipatah-patah (Cissus quadrangularis Salisb) extract administration on osteoclast formation and osteoporosis treatment in female rats during post menopausal period

Dublin Core

Title

The effect of sipatah-patah (Cissus quadrangularis Salisb) extract administration on osteoclast formation and osteoporosis treatment in female rats during post menopausal period

Description

Cissus quadrangularis Linn (Cq) is a rambling shrub, characterized by a thick quadrangular fleshy stem and widely used to cope with joint pain, syphilis, venereal disease, and osteoporosis. This plant is containing calcium, phosphate and phyto-oestrogens. Hence the objective of the present study was to evaluate effect of the C. quadrangularis on bone recovery of rat. Blood was drawn once each 30 days to analyze serum calcium and phosphate concentration in blood. Rats were sacrificed to analyze bone histology.  Os tibia fibula slice was stained with Hematoxylin Eosin (HE) method to observe osteoblast and osteoclast density, and Masson trichrome to observe trabeculae structure. ESP administration at longer period on treatment rats (OV-2) leads to more radiopaque  bone mass than other groups including control group  but osteoclast density is lower

Creator

Sabri, M.

Source

Proceedings of The Annual International Conference, Syiah Kuala University - Life Sciences & Engineering Chapter; Vol 1, No 1 (2011): Life Sciences
2089-208X

Publisher

Syiah Kuala University

Date

2011-12-15

Relation

http://jurnal.unsyiah.ac.id/AICS-SciEng/article/view/1921/1849

Format

application/pdf

Language

eng

Type

info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article

Identifier

http://jurnal.unsyiah.ac.id/AICS-SciEng/article/view/1921